Mouse Aimp2 activation kit by CRISPRa
CAT#: GA214309
Aimp2 CRISPRa kit - CRISPR gene activation of mouse aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Aimp2 |
Locus ID | 231872 |
Kit Components | GA214309G1, Aimp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214309G2, Aimp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214309G3, Aimp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001172146, NM_146165 |
Synonyms | AA407136; AA407225; Aimp2(p38); Jtv1 |
Summary | Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:12060739). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation (PubMed:12819782). Blocks MDM2-mediated ubiquitination and degradation of p53/TP53 (PubMed:18695251). Functions as a proapoptotic factor (PubMed:16135753).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN501046 | Aimp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |