Mouse Pogz activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pogz
Locus ID	229584
Kit Components	GA214087G1, Pogz gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214087G2, Pogz gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214087G3, Pogz gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001165948, NM_172683, NM_001368811, NM_001368812
Synonyms	9530006B08Rik
Summary	Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (By similarity).[UniProtKB/Swiss-Prot Function]

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