Mouse Slc25a44 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc25a44
Locus ID	229517
Kit Components	GA214078G1, Slc25a44 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214078G2, Slc25a44 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214078G3, Slc25a44 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145876, NM_001145877, NM_001281795, NM_178696, NR_027357, NM_001357749
Synonyms	6720482A19; B430110G05Rik
Summary	Mitochondrial solute transporter which transports branched-chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue (BAT) (PubMed:31435015). BAT is involved in BCAA catabolism and actively utilizes BCAA in the mitochondria for thermogenesis (PubMed:31435015).[UniProtKB/Swiss-Prot Function]

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