Mouse Smg7 activation kit by CRISPRa
CAT#: GA213865
Smg7 CRISPRa kit - CRISPR gene activation of mouse Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Smg7 |
Locus ID | 226517 |
Kit Components | GA213865G1, Smg7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213865G2, Smg7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213865G3, Smg7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001005507, NM_001160256, NM_001160257, NM_001359257 |
Synonyms | 9430023P16Rik; mKIAA0250 |
Summary | Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN516313 | Smg7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |