Mouse Adamts10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adamts10
Locus ID	224697
Kit Components	GA213715G1, Adamts10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213715G2, Adamts10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213715G3, Adamts10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172619, NR_037707, NR_037708, NR_137626, NR_137627, NR_137628, NR_137629
Synonyms	9430006O18; Adam-ts10; Adamts-10; AW045948; Znmp
Summary	This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate a functional, zinc-dependent metallopeptidase enzyme. [provided by RefSeq, Jul 2016]

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