Mouse Ilrun activation kit by CRISPRa
CAT#: GA213706
Ilrun CRISPRa kit - CRISPR gene activation of mouse inflammation and lipid regulator with UBA-like and NBR1-like domains
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Ilrun |
Locus ID | 224647 |
Kit Components | GA213706G1, Ilrun gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213706G2, Ilrun gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213706G3, Ilrun gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001033279, NM_001044719, NM_001271511 |
Synonyms | AU020189; C030010A15; C80239 |
Summary | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
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