Mouse Zfp322a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfp322a
Locus ID	218100
Kit Components	GA213526G1, Zfp322a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213526G2, Zfp322a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213526G3, Zfp322a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001111107, NM_001286155, NM_001286156, NM_172586
Synonyms	Znf322; Znf322a
Summary	Transcriptional activator. Important for maintenance of pluripotency in embryonic stem cells. Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes. Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly. Promotes inhibition of MAPK signaling during embryonic stem cell differentiation.[UniProtKB/Swiss-Prot Function]

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