Mouse Gls2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gls2
Locus ID	216456
Kit Components	GA213356G1, Gls2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213356G2, Gls2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213356G3, Gls2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033264, NM_001285777, NM_001285779
Synonyms	A330074B06Rik; AI195532; GA; GLS; Lga
Summary	Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.[UniProtKB/Swiss-Prot Function]

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