Mouse Plekhh2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plekhh2
Locus ID	213556
Kit Components	GA213165G1, Plekhh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213165G2, Plekhh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213165G3, Plekhh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_177606, NM_001357986, NM_001357987
Synonyms	AI256725; E030001K05; mKIAA2028
Summary	In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.[UniProtKB/Swiss-Prot Function]

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