Mouse Dstyk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dstyk
Locus ID	213452
Kit Components	GA213153G1, Dstyk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213153G2, Dstyk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213153G3, Dstyk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172516
Synonyms	A930019K20Rik; C430014H23Rik; C820013G01; Ripk5
Summary	Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.[UniProtKB/Swiss-Prot Function]

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