Mouse Nek11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nek11
Locus ID	208583
Kit Components	GA212871G1, Nek11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212871G2, Nek11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212871G3, Nek11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172461
Synonyms	4932416N14Rik
Summary	Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.[UniProtKB/Swiss-Prot Function]

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