Mouse Yeats2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Yeats2
Locus ID	208146
Kit Components	GA212845G1, Yeats2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212845G2, Yeats2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212845G3, Yeats2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033237, NM_001145930, NM_001145931
Synonyms	BC042768; mKIAA1197
Summary	Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.[UniProtKB/Swiss-Prot Function]

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