Mouse Klf11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Klf11
Locus ID	194655
Kit Components	GA212770G1, Klf11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212770G2, Klf11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212770G3, Klf11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_178357
Synonyms	9830142A17; D12Ertd427e; Tieg2; Tieg2b; Tieg3
Summary	Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites inhibiting cell growth (By similarity). Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.[UniProtKB/Swiss-Prot Function]

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