Mouse Hps4 activation kit by CRISPRa
CAT#: GA212717
Hps4 CRISPRa kit - CRISPR gene activation of mouse HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Hps4 |
Locus ID | 192232 |
Kit Components | GA212717G1, Hps4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212717G2, Hps4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212717G3, Hps4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_138646, NM_001359853 |
Synonyms | 2010205O06Rik; AU040608; BLOC-3; C130020P05Rik; le; mKIAA1667 |
Summary | Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN507929 | Hps4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |