Mouse Hps4 activation kit by CRISPRa

CAT#: GA212717

Hps4 CRISPRa kit - CRISPR gene activation of mouse HPS4, biogenesis of lysosomal organelles complex 3 subunit 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Hps4
Locus ID 192232
Kit Components

GA212717G1, Hps4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212717G2, Hps4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212717G3, Hps4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_138646, NM_001359853
Synonyms 2010205O06Rik; AU040608; BLOC-3; C130020P05Rik; le; mKIAA1667
Summary Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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