Mouse Bbc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bbc3
Locus ID	170770
Kit Components	GA212608G1, Bbc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212608G2, Bbc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212608G3, Bbc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_133234
Synonyms	PUMA; PUMA/JFY1
Summary	Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53 (By similarity). Regulates ER stress-induced neuronal apoptosis.[UniProtKB/Swiss-Prot Function]

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