Mouse Acbd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Acbd3
Locus ID	170760
Kit Components	GA212601G1, Acbd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212601G2, Acbd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212601G3, Acbd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_133225
Synonyms	60kDa; 8430407O11Rik; D1Ertd10e; GCP60; Gocap1; GOLPH1; Pap7
Summary	Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (By similarity). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (PubMed:12711385). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase (By similarity).[UniProtKB/Swiss-Prot Function]

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