Mouse Kcnn3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnn3
Locus ID	140493
Kit Components	GA212512G1, Kcnn3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212512G2, Kcnn3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212512G3, Kcnn3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_080466
Synonyms	KCa2.3; SK3; SKCA3
Summary	Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity).[UniProtKB/Swiss-Prot Function]

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