Mouse Rims1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rims1
Locus ID	116837
Kit Components	GA212454G1, Rims1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212454G2, Rims1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212454G3, Rims1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001012623, NM_001012624, NM_001012625, NM_053270, NM_183018
Synonyms	C030033M19Rik; mKIAA0340; Rab3ip1; Rim; RIM1; RIM1a; RIM1alpha; Serg1
Summary	Rab effector involved in exocytosis (PubMed:11797009). May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (PubMed:11797009). Plays a role in dendrite formation by melanocytes (By similarity).[UniProtKB/Swiss-Prot Function]

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