Mouse Erc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Erc1
Locus ID	111173
Kit Components	GA212378G1, Erc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212378G2, Erc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212378G3, Erc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_053204, NM_178085, NR_104484
Synonyms	4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST2; ELKS; Elks1
Summary	Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.[UniProtKB/Swiss-Prot Function]

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