Mouse Mmadhc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mmadhc
Locus ID	109129
Kit Components	GA212189G1, Mmadhc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212189G2, Mmadhc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212189G3, Mmadhc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_133839, NM_001348198, NM_001348199, NM_001348200
Synonyms	2010311D03Rik; AI314967; CblD
Summary	Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC.[UniProtKB/Swiss-Prot Function]

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