Mouse Mat2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mat2b
Locus ID	108645
Kit Components	GA212114G1, Mat2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212114G2, Mat2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212114G3, Mat2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199274, NM_134017
Synonyms	1110064C04Rik; 2410018D16Rik; AI182287; AU022853; MAT-II; MATIIbeta; TGR
Summary	Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro).[UniProtKB/Swiss-Prot Function]

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