Mouse Magee1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Magee1
Locus ID	107528
Kit Components	GA212006G1, Magee1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212006G2, Magee1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212006G3, Magee1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_053201
Synonyms	AI847422; DAMAGE; mMage-e1
Summary	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (By similarity).[UniProtKB/Swiss-Prot Function]

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