Mouse Ece2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ece2
Locus ID	107522
Kit Components	GA212003G1, Ece2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212003G2, Ece2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212003G3, Ece2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_139293, NM_177942
Synonyms	1810009K13Rik; 6330509A19Rik; 9630025D12Rik; BB127715; Ece-2
Summary	Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides (By similarity). May play a role in amyloid-beta processing (PubMed:12464614).[UniProtKB/Swiss-Prot Function]

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