Mouse Prickle1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prickle1
Locus ID	106042
Kit Components	GA211914G1, Prickle1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211914G2, Prickle1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211914G3, Prickle1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033217, NM_001364846
Synonyms	1110058P22Rik; AW215793; b2b019Clo; mpk1; Prickle
Summary	Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity). Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor (By similarity).[UniProtKB/Swiss-Prot Function]

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