Mouse Espl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Espl1
Locus ID	105988
Kit Components	GA211909G1, Espl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211909G2, Espl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211909G3, Espl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001014976, NM_001356312
Synonyms	AL024103; AU045071; Cerp; ESP1; PRCE; SSE
Summary	Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms (By similarity).[UniProtKB/Swiss-Prot Function]

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