Mouse Tmem98 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem98
Locus ID	103743
Kit Components	GA211761G1, Tmem98 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211761G2, Tmem98 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211761G3, Tmem98 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029537
Synonyms	6530411B15Rik; AI463522
Summary	Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation (PubMed:25946230). The secreted form promotes differentiation of T helper 1 cells (Th1) (PubMed:25946230).[UniProtKB/Swiss-Prot Function]

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