Mouse Csnk1a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Csnk1a1
Locus ID	93687
Kit Components	GA211312G1, Csnk1a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211312G2, Csnk1a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211312G3, Csnk1a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_146087, NM_001357498, NM_001357499, NM_001357500
Synonyms	2610208K14Rik; 4632404G05Rik; 5430427P18Rik; CK1a; Csnk1a
Summary	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (By similarity).[UniProtKB/Swiss-Prot Function]

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