Mouse Ndst3 activation kit by CRISPRa
CAT#: GA211212
Ndst3 CRISPRa kit - CRISPR gene activation of mouse N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Ndst3 |
Locus ID | 83398 |
Kit Components | GA211212G1, Ndst3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211212G2, Ndst3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211212G3, Ndst3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001293682, NM_031186, NR_121616 |
Synonyms | 4921531K01Rik; 4930511P15Rik; N-HSST 3; NDST-3 |
Summary | Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN510818 | Ndst3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |