Mouse Celf3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Celf3
Locus ID	78784
Kit Components	GA211034G1, Celf3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211034G2, Celf3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211034G3, Celf3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001289613, NM_001289616, NM_001289620, NM_172434, NR_110353, NM_001357784, NM_001357785, NM_001357786, NM_001357787, NR_151857
Synonyms	4930415M08Rik; BRUNOL1; CAGH4; ERDA4; Tnrc4
Summary	RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA (By similarity).[UniProtKB/Swiss-Prot Function]

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