Mouse Sbf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sbf1
Locus ID	77980
Kit Components	GA210854G1, Sbf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210854G2, Sbf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210854G3, Sbf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081030, NM_001170561, NM_030019
Synonyms	2610510A08Rik; B230113C15Rik; mKIAA3020; Mtmr5
Summary	Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.[UniProtKB/Swiss-Prot Function]

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