Mouse Dcun1d5 activation kit by CRISPRa
CAT#: GA210637
Dcun1d5 CRISPRa kit - CRISPR gene activation of mouse DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Dcun1d5 |
Locus ID | 76863 |
Kit Components | GA210637G1, Dcun1d5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210637G2, Dcun1d5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210637G3, Dcun1d5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_029775, NM_001357483, NM_001357484 |
Synonyms | 3110001A18Rik; 4833420K19Rik; AW060460; D430047L21Rik |
Summary | Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate to cell proliferation and anchorage-independent cell growth.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN504352 | Dcun1d5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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