Mouse Dcun1d5 activation kit by CRISPRa

CAT#: GA210637

Dcun1d5 CRISPRa kit - CRISPR gene activation of mouse DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Dcun1d5
Locus ID 76863
Kit Components

GA210637G1, Dcun1d5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA210637G2, Dcun1d5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA210637G3, Dcun1d5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_029775, NM_001357483, NM_001357484
Synonyms 3110001A18Rik; 4833420K19Rik; AW060460; D430047L21Rik
Summary Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate to cell proliferation and anchorage-independent cell growth.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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