Mouse Srxn1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Srxn1
Locus ID	76650
Kit Components	GA210571G1, Srxn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210571G2, Srxn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210571G3, Srxn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029688
Synonyms	1700127B04Rik; AI854065; AW488194; Npn3; Srx; Srx1; TX01
Summary	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.[UniProtKB/Swiss-Prot Function]

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