Mouse Mib2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mib2
Locus ID	76580
Kit Components	GA210548G1, Mib2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210548G2, Mib2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210548G3, Mib2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256107, NM_001256108, NM_001256110, NM_145124, NM_001369161, NM_001369162, NM_001369163, NM_001369164, NM_001369165, NM_001369166, NM_001369167, NM_001369168
Synonyms	2210008I11Rik; skd; Zzank1
Summary	E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.[UniProtKB/Swiss-Prot Function]

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