Mouse Ccdc134 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccdc134
Locus ID	76457
Kit Components	GA210514G1, Ccdc134 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210514G2, Ccdc134 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210514G3, Ccdc134 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001326588, NM_172428, NR_137170
Synonyms	2310042L06Rik; AW208859
Summary	In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling.[UniProtKB/Swiss-Prot Function]

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