Mouse Zdhhc20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zdhhc20
Locus ID	75965
Kit Components	GA210411G1, Zdhhc20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210411G2, Zdhhc20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210411G3, Zdhhc20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029492, NM_001360097, NM_001360098
Synonyms	4930542A17Rik; 5033406L14Rik; AI448102; B230110O18Rik; ENSMUSG00000055956; HK11
Summary	Catalyzes palmitoylation of Cys residues on target proteins (PubMed:15603741). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains (By similarity).[UniProtKB/Swiss-Prot Function]

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