Mouse Rnf19b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf19b
Locus ID	75234
Kit Components	GA210136G1, Rnf19b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210136G2, Rnf19b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210136G3, Rnf19b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029219, NM_001368763
Synonyms	4930534K13Rik; 4930555L03Rik; Ibrdc3
Summary	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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