Mouse P4htm activation kit by CRISPRa
CAT#: GA209889
P4htm CRISPRa kit - CRISPR gene activation of mouse prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | P4htm |
Locus ID | 74443 |
Kit Components | GA209889G1, P4htm gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209889G2, P4htm gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209889G3, P4htm gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_028944, NM_001357465, NR_151688 |
Synonyms | 4933406E20Rik; AI853847; BB128974; Ph-4 |
Summary | Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN512727 | P4htm - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |