Mouse Ttll11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttll11
Locus ID	74410
Kit Components	GA209872G1, Ttll11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209872G2, Ttll11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209872G3, Ttll11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_028921, NM_029774
Synonyms	4932702F08Rik; 4933424A20Rik; AU043211; D2Ertd624e; RP23-206J10.1
Summary	Polyglutamase which preferentially modifies alpha-tubulin (PubMed:17499049). Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Required for CCSAP localization to both spindle and cilia microtubules (PubMed:17499049). Generates long side-chains (PubMed:20530212).[UniProtKB/Swiss-Prot Function]

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