Mouse Psd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Psd
Locus ID	73728
Kit Components	GA209594G1, Psd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209594G2, Psd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209594G3, Psd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347454, NM_028627
Synonyms	1110007H17Rik; A930015K15; Efa6; Efa6a; mKIAA2011; Psdl
Summary	Guanine nucleotide exchange factor for ARF6 (By similarity). Isoform 2 and isoform 3 induce cytoskeletal remodeling, but lead to distinct morphological changes in HeLa cells: isoform 2 induces cell elongation and formation of actin-rich protrusions, whereas isoform 3 promotes the formation of membrane ruffles and loss of stress fibers (PubMed:19494129).[UniProtKB/Swiss-Prot Function]

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