Mouse Taf4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Taf4b
Locus ID	72504
Kit Components	GA209256G1, Taf4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209256G2, Taf4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209256G3, Taf4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001100449, NM_001369357, NM_001369358
Synonyms	105kDa; 2610524B04Rik; 4932409F03Rik; AW987595; Taf2c2; TAFII-105; TAFII105
Summary	Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators asond repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis.[UniProtKB/Swiss-Prot Function]

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