Mouse Tmem175 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem175
Locus ID	72392
Kit Components	GA209224G1, Tmem175 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209224G2, Tmem175 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209224G3, Tmem175 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001163531, NM_001163532, NM_028223, NM_001359423, NM_001359426, NM_001359427
Synonyms	3010001K23Rik; AI504381; mTMEM175
Summary	Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.[UniProtKB/Swiss-Prot Function]

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