Mouse Nkd2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkd2
Locus ID	72293
Kit Components	GA209187G1, Nkd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209187G2, Nkd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209187G3, Nkd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347535, NM_028186
Synonyms	2210403L10Rik; AW212591; mNkd2
Summary	Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells (By similarity).[UniProtKB/Swiss-Prot Function]

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