Mouse Alkbh4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alkbh4
Locus ID	72041
Kit Components	GA209071G1, Alkbh4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209071G2, Alkbh4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209071G3, Alkbh4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347492, NM_028070, NM_001359414, NM_001359415, NM_001359416, NM_001359417
Synonyms	2010004B12Rik; Abj4
Summary	Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation (By similarity).[UniProtKB/Swiss-Prot Function]

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