Mouse Fbxo22 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo22
Locus ID	71999
Kit Components	GA209053G1, Fbxo22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209053G2, Fbxo22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209053G3, Fbxo22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_028049
Synonyms	0610033L19Rik; 1600016C16Rik
Summary	Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.[UniProtKB/Swiss-Prot Function]

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