Mouse Rnf135 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf135
Locus ID	71956
Kit Components	GA209032G1, Rnf135 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209032G2, Rnf135 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209032G3, Rnf135 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_028019
Synonyms	0610037N03Rik; 2410006N06Rik
Summary	Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.[UniProtKB/Swiss-Prot Function]

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