Mouse Mus81 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mus81
Locus ID	71711
Kit Components	GA208905G1, Mus81 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208905G2, Mus81 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208905G3, Mus81 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027877, NR_153768, NR_153769
Synonyms	1200008A18Rik; AI182501; AW045863
Summary	Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.[UniProtKB/Swiss-Prot Function]

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