Mouse Mcm10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mcm10
Locus ID	70024
Kit Components	GA208398G1, Mcm10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208398G2, Mcm10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208398G3, Mcm10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001305259, NM_027290
Synonyms	2410041F14Rik; AU018508; C79164; C330019M07Rik
Summary	Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (By similarity).[UniProtKB/Swiss-Prot Function]

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