Mouse Rhou activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rhou
Locus ID	69581
Kit Components	GA208234G1, Rhou gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208234G2, Rhou gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208234G3, Rhou gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_133955
Synonyms	2310026M05Rik; AI182090; Arhu; CDC42L1; G28K; mG28K; WRCH-1; WRCH1
Summary	Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity).[UniProtKB/Swiss-Prot Function]

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