Mouse Disp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Disp1
Locus ID	68897
Kit Components	GA207971G1, Disp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207971G2, Disp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207971G3, Disp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001278218, NM_001278219, NM_001278220, NM_026866
Synonyms	1190008H24Rik; DispA
Summary	Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (PubMed:22902404).[UniProtKB/Swiss-Prot Function]

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