Mouse Flnc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Flnc
Locus ID	68794
Kit Components	GA207937G1, Flnc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207937G2, Flnc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207937G3, Flnc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081185, NM_001311074, NM_026839
Synonyms	1110055E19Rik; ABP-280; ABPL; Fln2
Summary	Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.[UniProtKB/Swiss-Prot Function]

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